Giant Cell-rich Osteosarcoma in Temporal Bone: Case Report and Literature Review

Objective: Describe the clinical, imageological, and pathological features of Giant cell-rich osteosarcoma (GCRO), as well as differential diagnosis. Case Presentation: We describe a 43-year-old patient with temporal bone GCRO who accidentally noticed a painless hard bump about the size of a finger in the left tempus a year ago. Imageological examination showed obvious swelling of the temporal bone, dissolving bony destruction, invasive growth, wide range of involvement, and obvious enhancement of the substantial part of the tumor (found by enhancement scanning). Pathological studies also revealed a large number of osteoclastlike giant cells in the background of osteosarcoma. Conclusion: GCRO can be easily misdiagnosed as GCT, and early diagnosis is very important for its prognosis. Clinically and imageologically, GCRO has certain characteristics but lacks specificity; thus, clinical, imageological, and pathological diagnoses should be integrated.